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pentobarbital will minimize the extent or influence of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.Most experiences of clinically significant drug interactions taking place Along with the barbiturates have involved phenobarbital. Nevertheless, the appliance of those data to other barbiturates appears vali

Barbiturates may cause fetal injury when administered into a pregnant woman. Retrospective, circumstance-managed studies have recommended a link in between the maternal usage of barbiturates and a greater than expected incidence of fetal abnormalities. Subsequent oral or parenteral administration, barbiturates conveniently cross the placental barri